Levofloxacin

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Missing image
Levofloxacin.png
Levofloxacin chemical structure


Levofloxacin

(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-
10-(4-methyl-1-piperazinyl)-7-oxo-
7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
CAS number
100986-85-4
ATC code
J01MA12, S01AX19
Chemical formula C18H20FN3O4
Molecular weight 361.371
Bioavailability  ?
Metabolism  ?
Elimination half-life  ?
Excretion  ?
Pregnancy category  ?
Legal status  ?
Routes of administration  ?

Levofloxacin is relatively new fluoroquinolone antibiotic, marketed by Ortho-McNeil under the brand name Levaquin. Chemically, Levofloxacin is the S-enantiomer (L-isomer) of ofloxacin.

Levofloxacin is effective against a number of gram-positive and gram-negative bacteria. Because of its broad spectrum of action, levofloxacin is frequently prescribed in hospitals for pulmonary infections before the specific causal organism is known. Once the causal organism is known, levofloxacin is discontinued and the patient is given a narrow-spectrum antibiotic.

Gram-positive bacteria

Gram-negative bacteria

Other

Some information extracted from Levaquin Prescribing information.Template:Pharma-stub

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