Muscle relaxant

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(Redirected from Muscle relaxants)

In medicine, a muscle relaxant is a drug that causes skeletal muscle contraction to cease. Muscle relaxants are used to facilitate surgery, to enable tracheal intubation and to facilitate mechanical ventilation.

Muscles relaxants typically work by blocking the effect of acetylcholine (ACh) at the neuromuscular junction.

Contents

Receptor blockers

Substances that compete with ACh, for the receptors on a muscle cell can be either depolarising, or non-depolarising.

Depolarising muscle relaxants activate the muscle briefly, before blocking it.

Non-depolarising relaxants block the ACh receptors without activating them.

Other mechanisms

Botulinum toxin, marketed as Botox for facial wrinkle removal, works by stopping the release of ACh from the presynaptic neuron.

Central acting muscle relaxants

Unclassified

There are several other skeletal muscle relaxants, which may belong in the above categories:

Acting on smooth muscle

Other

Drugs from classes other than the muscle relaxant class are also used to treat spasticity:

See also

External references

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